Shengliang Zhang Selected Research

Cisplatin (Platino)

5/2024	Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure.
9/2021	Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells.

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Shengliang Zhang Research Topics

Disease

20	Neoplasms (Cancer) 05/2024 - 12/2012
5	Colorectal Neoplasms (Colorectal Cancer) 09/2021 - 09/2015
4	Infections 05/2024 - 09/2020
3	Carcinogenesis 05/2024 - 09/2015
3	COVID-19 05/2024 - 09/2020
2	Colonic Neoplasms (Colon Cancer) 10/2021 - 02/2014
2	Disease Progression 11/2020 - 09/2020
2	Lung Neoplasms (Lung Cancer) 11/2020 - 09/2020
1	Virus Diseases (Viral Diseases) 05/2024
1	Residual Neoplasm 01/2023
1	Bacterial Infections (Bacterial Infection) 02/2022
1	Carcinoma (Carcinomatosis) 10/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 09/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	Conversion Disorder (Astasia Abasia) 12/2019
1	Neoplasm Metastasis (Metastasis) 09/2017
1	Hypoxia (Hypoxemia) 01/2014
1	Squamous Cell Carcinoma of Head and Neck 03/2006

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 05/2024 - 12/2012
4	CytokinesIBA 01/2023 - 09/2020
3	Irinotecan (Camptosar)FDA LinkGeneric 09/2021 - 09/2015
2	Cisplatin (Platino)FDA LinkGeneric 05/2024 - 09/2021
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2014
2	1- (4- methylpiperazin- 1- yl)- 3- (5- nitrofuran- 2- yl)prop- 2- en- 1- oneIBA 01/2022 - 09/2015
2	Fluorouracil (Carac)FDA LinkGeneric 09/2021 - 09/2017
2	Peptide Hydrolases (Proteases)FDA Link 11/2020 - 09/2020
2	Antiviral Agents (Antivirals)IBA 11/2020 - 09/2020
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 11/2020 - 09/2020
2	Interleukin-6 (Interleukin 6)IBA 11/2020 - 09/2020
2	CB002IBA 01/2018 - 09/2017
2	ProdigiosinIBA 01/2016 - 02/2014
1	SARS-CoV-2 spike proteinIBA 05/2024
1	mRNA VaccinesIBA 05/2024
1	DNA (Deoxyribonucleic Acid)IBA 05/2024
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 05/2024
1	Death Domain ReceptorsIBA 05/2024
1	Circular RNAIBA 12/2023
1	VaccinesIBA 01/2023
1	ethidium homodimerIBA 01/2023
1	LigandsIBA 01/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 02/2022
1	Anti-Infective Agents (Microbicides)IBA 02/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 10/2021
1	pembrolizumabIBA 10/2021
1	Interleukin-8 (Interleukin 8)IBA 09/2021
1	Histones (Histone)IBA 09/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 09/2021
1	Ferritins (Ferritin)IBA 09/2021
1	ONC212IBA 01/2021
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 11/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	SolutionsIBA 12/2019
1	polysulfideIBA 12/2019
1	Apoptosis Regulatory ProteinsIBA 01/2018
1	matrigelIBA 09/2017
1	Oxygen (Dioxygen)IBA 07/2017
1	LuciferasesIBA 01/2016
1	Caspase 8 (Caspase-8)IBA 03/2006

Therapy/Procedure

14	Therapeutics 05/2024 - 12/2012
3	Drug Therapy (Chemotherapy) 05/2024 - 05/2016
3	Immunotherapy 01/2023 - 10/2021
1	Adjuvant Chemotherapy 01/2023
1	Radiotherapy 09/2015